RENAL L-2-HYDROXYGLUTARATE DEHYDROGENASE ACTIVITY PROMOTES HYPOXIA TOLERANCE AND MITOCHONDRIAL METABOLISM IN DROSOPHILA MELANOGASTER

Renal L-2-hydroxyglutarate dehydrogenase activity promotes hypoxia tolerance and mitochondrial metabolism in Drosophila melanogaster

Objectives: The mitochondrial enzyme L-2-hydroxyglutarate dehydrogenase (L2HGDH) regulates the abundance of L-2-hydroxyglutarate (L-2HG), a potent signaling metabolite capable of influencing chromatin architecture, mitochondrial metabolism, and cell fate decisions.Loss of L2hgdh activity in humans induces ectopic L-2HG accumulation, resulting in ne

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On the Origin of Post-Aspirated Stops: Production and Perception of /s/ + Voiceless Stop Sequences in Andalusian Spanish

The Tables present study investigates the role of articulatory and perceptual factors in the change from pre- to post-aspiration in two varieties of Andalusian Spanish.In an acoustic study, the influence of stop type, speaker age, and variety on the production of pre- and post-aspiration was analyzed in isolated words produced by 24 speakers of a W

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Functional outcomes of bowel resection versus shaving or disc excision of colorectal endometriosis: a systematic review protocol

Introduction Endometriosis is a prevalent gynaecological condition for women of reproductive age worldwide.While endometriosis primarily involves the reproductive system, it can also infiltrate additional viscera such as the gastrointestinal tract.Patients with colorectal endometriosis can have severe symptoms that require surgical intervention.The

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Status and identity of law librarianship in Nigeria

This paper investigates the THICKEFY FOAM status and identity of law librarians in Nigeria.The objective is to identify, discuss and review literature on the educational requirements, professional regulation, labour market, salaries, associations, labour union and research study of the law librarians.The population for this study consists of six in

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